Al-Ghamdi has served as Imam to Muslim communities across the globe, and is currently the Imam of Kanoo Mosque in Dammam, Saudi Arabia. Al-Ghamdi studied the fundamentals of Islam and hadith transmission, and is recognized as an influential Saudi theologian. In 2009, he was appointed by royal decree as a co-imam for the taraweeh prayers in the Al-Haram Al-Madani in Madinah.